Publications

Research & Publications

Dr Humayun has a special interest in the management of thyroid diseases and reproductive endocrinology including sexual dysfunction. He is also interested in diabetes care, especially type 1 diabetes, and the clinical use of new technologies, including insulin pumps and continuous glucose monitoring to improve patient outcomes.

Outside of his consultancy work, Dr. Humayun has completed several research projects and has published several papers relating to his work. Here are a few of his recently published articles:

Principal Investigator in Ongoing Research Trials:

Start Right study which aims to achieve more accurate classification of diabetes and identification of best treatment option early on.
UK-EDI study: Early Detection of Pancreatic Cancer
DRoPLeT study: Detection of pancreatic beta cell functions in adults with recent diagnosis of T1D
SIRONA Trial: First in human study of SIRONA: A study to determine safety feasibility and tolerability of an expanding hydrogel tablet, designed to promote weight loss in adults with a body mass index of 30-40.

The list of publications is as below:

Humayun MA et al, When the Gold standard test poses a diagnostic challenge – Choosing the correct assay. (BMJ Case Reports – in press)
Humayun MA et al, Pituitary Dysfunction with anormal Pituitary – Where to look for? (BMJ Case Reports – in press)
TRLS-D-24-00853 Evaluating the effectiveness of a digital health and financial incentive intervention to promote physical activity in patients living with type 2 diabetes: Study protocol for a randomised controlled trial with a nested qualitative study: ACTIVATE Trial James Sanders; Amanda Daley; Dale Esliger; Andrea Roalfe; Antoanela Colda; Joanne Turner; Soma Hajdu; Andrew Potter; Asif Malik Humayun; Ioannis Spiliotis; Ian Reckless; Oliver Mytton (Trials)
Naseer, Khulla & Qazi, Javaria & Qazi, Atika & Avuglah, Bright & Tahir, Rabail & Rasheed, Rasheed & Khan, Shah Khalid & Khan, Baseer & Zeeshan, Muhammad & Humayun, Asif Malik & Naseem, Usman. (2021). Travel behaviour prediction amid covid-19 underlaying situational awareness theory and health belief model. Behaviour and Information Technology.
Barnett M, Ahmed F, Mihai R, Rattan A, Humayun MA. The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature. Case Rep Endocrinol. 2021 May.
Humayun MA et al. Structured Diabetes Education – An unmet need in Pakistan. JPSIM 1; Nov 2020.
Humayun MA, Jenkins E, Knott J, Ryder J, Shaban C, Weiss M, Charman J, Cavan D, Brooks A. Intensive structured education for type 1 diabetes management using BERTIE: Long-term follow-up to assess impact on glycaemic control and quality of life indices. Diabetes Res Clin Pract. 2018 Sep;143:275-281. doi: 10.1016/j.diabres.2018.07.034. PMID: 30076871.
Humayun MA, Cranston I. In-patient Tolvaptan use in SIADH: care audit, therapy observation and outcome analysis. BMC Endocrine Disorders. 2017;17:69. doi:10.1186/s12902-017-0214-2.
Humayun MA, Hart T, Richardson T. Cyclical Cushing’s: how best to catch the ups and downs. BMJ Case Rep. 2017 Jul 13;2017. pii: bcr-2016-218451. doi: 10.1136/bcr-2016-218451. PubMed PMID: 28705797.
Whicher, C. A., Humayun, M., Jenkins, E., Brooks, M., Benbow, M., Critoph, C. and Partridge, H. (2017), Evaluating insulin pump functionality during ionising radiation exposure. Pract Diab, 34: 306–308. doi:10.1002/pdi.2142
Humayun MA, Richardson T, Brooks A. Pyrexia of unknown origin in a patient initially presenting with traveler’s diarrhea. BMJ Case Reports 2016; doi:10.1136/bcr-2016-216654
Humayun MA, Partridge H. Insulin Pump – Choosing the right one for you. Diabetes Research & Wellness Foundation, Nov 2016.
Humayun MA, Rance C, Partridge H, Richardson T. An Unusual case of AKI. British Journal of Hospital Medicine, Aug 2016.
Humayun MA, Masding M. An Unusual Case of Recurrent Severe Hypoglycemia in a female With Type 1 Diabetes Undergoing Medically Assisted Abortion. Clinical Diabetes. Jul 2016, 34 (3) 161-163.
Humayun MA, Poole R. Monoclonal Antibodies and Multiple Immune Toxicities. Hormones Vol 15 No 2, Apr-June 2016
Humayun MA, Partridge H. Insulin Pump – Beyond Multiple Daily Injections. Diabetes Research & Wellness Foundation, June 2016.
Curtis L, Humayun MA, Walker J, Hampton K, Partridge H. Addition of SGLT2-inhibitor to GLP-1 agonist therapy in people with type 2 diabetes and sub-optimal glycemic control. Practical Diabetes Vol 33 No 4, May 2016
Humayun MA, Meeking D. Improving a diabetes foot service to prevent amputations: Portsmouth experience. British Journal of Diabetes Vascular Disease 2015;15:180-183
Haider Z, Ahmad FZ, Mahmood A, Waseem T, Shafiq I, Raza T, Qazi J, Siddique N, Humayun MA. Dengue fever in Pakistan: a paradigm shift; changing epidemiology and clinical patterns. Perspectives In Public Health. 2015 Sep 4.
Humayun MA, Meeking D. The Portsmouth Diabetic Foot Service. Diabetes Voice. Summer 2014; Issue 26
Humayun MA, Masood A, Mahmood A, Ahmad FZ, Waseem T. An unusual cause of stroke in a young female: a case report. The American Journal of Emergency Medicine. Volume 32, Issue 6, Pages A1-A8, 493-692.
Mehmood A, Waseem T, Humayoun MA. Measuring Partial Pressure of Ammonia in Arterial or Venous Blood VS total Ammonia Levels in Hepatic Encephalopathy. Gastroenterology & Hepatology Research, Vol 2, No 4 (2013).
Rajendran R, Humayun M, Richardson T. Escherichia coli and mycotic thoracic aortic aneurysm: a case report.. Grand Rounds, Vol 12, pages 27-31.
Afzal M.N, Humayun MA, Waseem T, Raza M.A, Masood A, Akram J. Serum Total Homocysteine Level; A True Cardiovascular Risk Factor Or An Acute Phase Reactant Protein? European Journal of Cardiovascular Medicine. July 2011, VOL I ISSUE II.
Azfar NA, Khan AR, Zia MA, Humayun MA, Malik LM, Jahangir M. Frequency of mucocutaneous manifestations in HIV positive Pakistani patients. Journal of Pakistan Association of Dermatologists 2011; 21 (3): 149-153.
Raza M.A, Qureshi U.F, Humayoun MA, Waseem T, Akram J. Effect of intravenous mannitol in mobilization of resistant cirrhotic ascites. European Journal of Gastroenterology and Hepatology: February 2011 – Volume 23 – Issue 2 – p 184–188.
Jawa,A.A.; Akram,J.; Sultan,M.; Humayoun,MA.; Raza,R. Nutrition-related vitamin B12 deficiency in patients in Pakistan with type 2 diabetes mellitus not taking metformin. Endocrine Practice. 2010 Mar-Apr;16(2):205-8.
Humayoun MA, Waseem T, Jawa AA, Hashmi MS, Akram J. Multiple dengue serotypes and high frequency of dengue hemorrhagic fever at two tertiary care hospitals in Lahore during the 2008 dengue virus outbreak in Punjab, Pakistan. International Journal of Infectious Diseases. 2010 Sep;14 Suppl 3:e54-9.
Javed A, Iqbal J, Humayoun MA. Etiological frequencies of transverse Myelopathy. A 3rd world scenario. Journal of Allama Iqbal Medical College Vol 7, No 3, Oct-Dec 2009
Humayoun MA, Riaz T, Jawa A, Sultan M, Sultan N, Bokhari SR, Akram J. First 100 days of the special HIV clinic at Jinnah Hospital, Lahore: clinical profile of drug-naive patients. Journal of Allama Iqbal Medical College Oct 2009; 7(3):12-3.
Humayun MA, Waseem T, Mahmood A, Raza A. Frequency of Risk factors for Ischemic Stroke in Young and Care Audit of In-Hospital Care Pathway at a Tertiary Care Hospital in Pakistan: JAIMC; Vol. 7, April-June 2009.
Humayoun M.A, Akram J. Dengue and Scientific Research in Pakistan. Journal of Allama Iqbal Medical College Vol 7, No 1, Jan-March 2009.

Papers in Process:

Dapagliflozin in T1 diabetes

Invited Lectures, Abstract Publications:

Management of Male Hypogonadism: 4th International Conference of Pakistan Society of Internal Medicine, March 2023
Locally Employed Doctors Support Program in Milton Keynes University Hospital, Multi-Specialty Conference of Medical Education Leaders (Abstract accepted), March 2023, Nottingham.
Shifting Paradigm in Diabetes Management: Cardio-Metabolic Summit, Royal College of Physicians London, October 2022
Approach to CGMs use in T1 Diabetes 2022
Use of Technology in Diabetes. Updates in Diabetes 2021
Diabetes & Fasting during Ramadan 2021
Live Webinar: Management of Hypercalcaemia – what a general physician needs to know. Post Graduate Institute Lahore 2020
Live Webinar: Rise of Machines in Diabetes & Virtual Management of Diabetes during the Pandemic, 2020
Live Webinar: Recent advancements in Diabetic Nephropathy – Milton Keynes Primary Care Network 2020
Live Webinar: Time in Range in Modern Times. East of England Diabetes Network 2020
Individualized Diabetes Care across all ages – Keeping it Safe and Simple. 6th Bedford Annual Diabetes Conference 2020
Medical Management of Obesity – Current Developments and Prospects. Pakistan Society of Internal Medicine Annual Conference, Lahore Pakistan 2020
Role of Sulfonylureas in resource-limited countries. Pakistan Society of Internal Medicine Annual Conference, Lahore Pakistan 2020
Getting to the Size of Matter – Diabetic Nephropathy. Milton Keynes Diabetes Conference 2018
Khan, Huma & Humayun, Asif Malik. (2019). Panhypopituitarism secondary to hypothalamic involvement in Isolated Langerhans cell Histiocytosis. Endocrine Abstracts. 10.1530/endoabs.65.P319.
Bolouri, Neda & Khan, Huma & Humayun, Asif Malik. (2019). The forgotten electrolyte-when hypercalcaemia presents with acute confusion. Endocrine Abstracts. 10.1530/endoabs.65.P124.
De-mystifying pharmacotherapy in T2DM – Holding back the tide of complications – Milton Keynes Diabetes Conference 2018
Diabetes Masterclass – Society for Acute Medicine Bournemouth 2018
Individualized Diabetes Care across all age – What is the evidence. Annual Milton Keynes Diabetes Conference
Aggressive Prolactinoma – A management challenge. Clinical Updates 2017
Multidisciplinary team secondary diabetes clinics (MDTSDC): a new role for the diabetes dietitian?. Diabetes UK 2017
Retrospective Analysis of Sub-Arachnoid Haemorrhage Diagnosis at a DGH – Accepted as poster presentation at European Congress of Internal Medicine 2016
Pyrexia of Unknown Origin – Initially presenting as Traveller’s Diarrhoea – Accepted as poster presentation at European Congress of Internal Medicine 2016
Usefulness of Adrenal Venous Sampling in ACTH-Independent Cushing’s. Poster presentation at Endo 2016
Development of a specialized service for the management of diabetes secondary to pancreatic insufficiency. Poster presentation at Diabetes UK Professional Conference 2016
Diabetes e-Learning Programme: A 10 Year Evaluation of the Usage and Effectiveness. Poster presentation at Diabetes UK Professional Conference 2016
A challenging case of Secondary Hypertension. Oral presentation at WEDA October 2015
Case presentation “Late endocrine effects of childhood cancer chemotherapy” Clinical updates 2014
A case series of “funny” thyroid function tests. Oral Presentation at Isle of Wight Endocrine day, Sep 2014
Long-term follow-up of patients with resistant hyponatremia; Poster presentation at ICE/ENDO 2014
Long-term follow-up of patients treated with Tolvaptan for resistant hyponatremia due to SIADH; poster presentation at BES 2014
Use of Tolvaptan for resistant hyponatremia due to SIADH; Oral Presentation at Wessex Endocrine and Diabetes Association
Spontaneous Resolution of Pituitary Cushing’s”, Poster presentation at BES 2013
Hypercalcemia secondary to granulomatous disorders- a series. Poster presentation at the SfE BES 2012
Hypoglycemia predating carcinomatosis-a diagnostic challenge. Poster presentation at SfE BES 2012
Dengue fever in Pakistan: a paradigm shift; changing epidemiology and clinical patterns. M.A. Humayun*. Oral presentation at the ECCMID meeting, London 2012
Two Unusual Presentations of Cushing’s disease; Oral Presentation at Isle of Wight Endocrine day, Sep 2014
A case of Hyponatremia due to Adrenal Metastasis Secondary to Squamous Cell Carcinoma of Skin; Oral Presentation at Isle of Wight Endocrine day, Sep 2014
“HIV in Pakistan”; 8th Advanced HIV Course, by European AIDS Clinical Society, Montpellier (France), September 8-10, 2010. (Oral Presentation)
“Multiple dengue serotypes and high frequency of dengue hemorrhagic fever during 2008 dengue virus outbreak in Punjab, Pakistan.” Oral presentation at the 19th Annual Meeting of MEDICAL RESEARCH SOCIETY OF PAKISTAN (MRSP)
Characteristics of a dengue virus outbreak in 2008 in Punjab; presented at 2nd AIMCAANA meeting Allama Iqbal Medical College Lahore 2008. (Oral Presentation)
Frequency of NASH in patients with Metabolic syndrome; presented at 2nd International Diabetes Conference 2008; Lahore. (Poster Presentation)
Hepatitis C in Pakistan; International Conference on Characterization and Management Of Emerging Viral Diseases In Developing World; 20-22 November 2006 at National Institute of Biotechnology and Genetic Engineering (NIBGE) Faisalabad Pakistan

Research & Publications

Principal Investigator in Ongoing Research Trials:

The list of publications is as below:

Papers in Process:

Invited Lectures, Abstract Publications:

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