
Obesity Research & Innovation
Helping develop the next generation of weight-management treatments. Dr Asif Malik Humayun combines extensive clinical experience with active Principal Investigator involvement in clinical research evaluating innovative obesity treatments.
Helping Develop the Next Generation of Weight-Management Treatments
Dr Asif Malik Humayun combines extensive clinical experience in obesity medicine with active involvement in clinical research evaluating innovative approaches to weight management.
He has served as Principal Investigator in clinical studies investigating SIRONA, a novel orally administered, gastro-retentive hydrogel treatment designed to support weight loss by promoting satiety and reducing dietary intake.
His involvement has included first-in-human research assessing safety, feasibility and tolerability, followed by proof-of-concept evaluation of efficacy and potential application in maintaining weight loss following GLP-1 treatment.
The SIRONA Research Programme
SIRONA is an investigational oral hydrogel treatment being studied as a potential non-systemic approach to weight management. Unlike medicines that act through absorption into the bloodstream, the investigational hydrogel is designed to expand within the gastrointestinal tract and promote a feeling of fullness.
The research programme has explored:
Important: SIRONA remains an investigational treatment and is not currently being offered as part of routine clinical care.
Dr Humayun's Role
As Principal Investigator, Dr Humayun has played a central clinical role in the delivery and evaluation of the SIRONA research programme. His responsibilities have included patient assessment, clinical oversight, treatment safety, interpretation of clinical outcomes and collaboration with the wider research team.
His involvement in both first-in-human and subsequent proof-of-concept research reflects his commitment to developing practical, scientifically robust treatments for people living with obesity.
Selected Research Involvement
44+
Publications
11,441+
Reads
451+
Citations
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